Dilip Morani*, Pravin Patil and Ashish Jain Pages 3 - 15 ( 13 )
Recently, nanotherapeutics has revolutionized the major impact on healthcare strategies and health facilities. Nanotherapeutics includes design, development and application of therapeutic agents having nano-size (1-100 nm). Due to implications in gene therapy and drug delivery, nanotherapeutics has received much interest in the current scenario. The major area where research is going on and giving maximum benefits from nano-based delivery system includes cancer diagnosis and targeting. The nanotherapeutics are designed in such a way that they will overcome the major drawbacks of conventional therapy and have multi-functionalities so that it can be targeted to cancer site. Nanotherapeutics have increased the permeability and retention of anticancer agents thereby targeting them to the tumor site. Nanotherapeutics has increased the effectiveness of anticancer agents with less or no toxicity. Likewise, diagnostic imaging is also possible with fluorescent nanoparticles based nanotherapeutics and has major potential applications in recent upcoming years with newer fluorescent nanomaterials for specific cancer targeting. NTs provided the possibility of delivering drugs to specific cells using nanoparticles. The overall drug consumption and side-effects may be lowered significantly by depositing the active agent in the morbid region only and in no higher dose than needed. Thus, attempts have been made to define the nanotherapeutics and to compile the latest developments in the field. Because the topic is of high importance to the general human wellbeing and covers recapitulation of cancer nanotherapeutics and summarizes and restates the main points of nanotherapeutics in the treatment of cancer disease.
Nanotherapeutics, Nanomedicine, Nanoparticles, Nanoformulation, Nanotechnology, Nanomaterials.
Shri D.D. Vispute College of Pharmacy and Research Center, Panvel, Maharashtra 421601, H.R. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra 425405, Shri D.D. Vispute College of Pharmacy and Research Center, Panvel, Maharashtra 421601